Minimal (one)modafinil will increase the level or outcome of pantoprazole by affecting hepatic enzyme CYP2C19 metabolism. Minimal/Importance Unfamiliar. Net effect on pantoprazole actions unfamiliar due to opposing outcomes of CYP450 enzymes; observeiloperidone raises amounts of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

Article Under Review